ChemicalBook--->CAS DataBase List--->1240398-17-7

1240398-17-7

1240398-17-7 Structure

1240398-17-7 Structure
IdentificationBack Directory
[Name]

Leukotriene D4-d5
[CAS]

1240398-17-7
[Synonyms]

Leukotriene D4-d5
YEESKJGWJFYOOK-HXHZKDJLSA-N
[Molecular Formula]

C25H40N2O6S
[MDL Number]

MFCD11045833
[MOL File]

1240398-17-7.mol
[Molecular Weight]

496.66
Chemical PropertiesBack Directory
[storage temp. ]

Store at -80°C
[solubility ]

DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): .1 mg/ml
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Description]

Leukotriene D4-d5 (LTD4-d5) is intended for use as an internal standard for the quantification of LTD4 by GC- or LC-MS. LTD4 is an active metabolite of LTC4 (Item Nos. 20210 | 10007241) and a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is formed via metabolism of LTC4 by γ-glutamyl transpeptidase. Like LTC4, LTD4 (0.01-0.1 pM) induces contractions in isolated guinea pig parenchymal strips and tracheal spirals. In vivo, LTD4 increases insufflation pressure, a marker of bronchoconstriction, in anesthetized guinea pigs by 100% when administered at a dose of 89 pmol per animal. It also increases vascular permeability in guinea pig skin when administered intradermally at a dose of 0.1 pmol per animal.
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