| Identification | Back Directory | [Name]
5-aminocarbonyl-10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5,10-imine | [CAS]
124070-15-1 | [Synonyms]
SGB017
SGB-017
SGB 017
5-aminocarbonyl-10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5,10-imine | [MDL Number]
MFCD00897934 | [MOL File]
124070-15-1.mol |
| Hazard Information | Back Directory | [Description]
ADCI, also known as SGB-017, is a glutamate receptor antagonist potentially for the treatment of epilepsy. ADCI blocks both voltage-activated sodium channels and N-methyl-D-aspartate (NMDA)-receptor-gated channels. Inhibition of sodium channels by ADCI was voltage dependent. High doses of ADCI increased dopamine metabolism in the prefrontal cortex and/or in the nucleus accumbens, but not in the dorsal striatum. |
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CHEMICAL LAND21
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