| Hazard Information | Back Directory | [Description]
Potent, ATP-competitive inhibitor of cyclin-dependent kinase (cdk) and casein kinase 1 (CK1) (IC50values are 220, 80 and 14 nM for cdk1/cyclin B, cdk5/p25 and CK1 respectively). Selective over GSK-3αβ(IC50= 4.1μM). Also shown to inhibit amyloid-βproduction in N2A-APP695cells. | [Uses]
(R)-DRF053 DiHydrochloride (cas# 1241675-76-2) is a useful research chemical.(R)-DRF053 Dihydrochloride was used for studying cancer treatments using combinations of CDK kinase and ERK inhibitors. | [storage]
Store at -20°C |
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| Company Name: |
BOC Sciences
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| Tel: |
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| Website: |
https://www.bocsci.com |
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