| Identification | Back Directory | [Name]
GSK-5498A | [CAS]
1253186-49-0 | [Synonyms]
GSK-5498A
(GSK5498A)
2,6-Difluoro-N-[1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-3-yl]benzamide
Benzamide, 2,6-difluoro-N-[1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-3-yl]- | [Molecular Formula]
C18H11F6N3O | [MDL Number]
MFCD28385869 | [MOL File]
1253186-49-0.mol | [Molecular Weight]
399.29 |
| Chemical Properties | Back Directory | [Boiling point ]
403.3±45.0 °C(Predicted) | [density ]
1.44±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : ≥ 100 mg/mL (250.44 mM);Water : < 0.1 mg/mL (insoluble) | [form ]
Solid | [pka]
10.81±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Definition]
ChEBI: GSK-5498A is a member of the class of pyrazoles that is 1H-pyrazole substituted by 2-fluoro-6-(trifluoromethyl)benzyl and (2,6-difluorobenzoyl)amino groups at positions 1 and 3, respectively. It is a inhibitor of Ca(2+) release-activated Ca(2+) (CRAC) channel and inhibits the release of mast cell mediators and T-cell cytokines in human and rat preparations. It has a role as a calcium channel blocker. It is a member of pyrazoles, a secondary carboxamide, a difluorobenzene and a member of (trifluoromethyl)benzenes. |
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| Company Name: |
Musechem
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| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
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