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1254475-87-0

1254475-87-0 Structure

1254475-87-0 Structure
IdentificationBack Directory
[Name]

BYIVGHIYNFQIJX-UHFFFAOYSA-N
[CAS]

1254475-87-0
[Synonyms]

BYIVGHIYNFQIJX-UHFFFAOYSA-N
JWH018 Pentanoic acid metabolite
JWH-018 N-Pentyl-5-carboxylic Acid
1H-Indole-1-pentanoic acid, 3-(1-naphthalenylcarbonyl)-
[Molecular Formula]

C24H21NO3
[MDL Number]

MFCD18382139
[MOL File]

1254475-87-0.mol
[Molecular Weight]

371.43
Chemical PropertiesBack Directory
[Boiling point ]

629.5±35.0 °C(Predicted)
[density ]

1.20±0.1 g/cm3(Predicted)
[solubility ]

DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml
[form ]

A crystalline solid
[pka]

4.73±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
Hazard InformationBack Directory
[Description]

JWH 018 is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor, derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding central cannabinoid (CB1) and CB2 receptors are 9.0 and 2.94 nM, respectively, for a CB1:CB2 ratio of 3.06. JWH 018 is one of several synthetic CBs which have been included in smoking mixtures. JWH 018 N-pentanoic acid metabolite is a minor urinary metabolite of JWH 018, characterized by carboxylation of the N-alkyl chain. In urine samples, this metabolite is almost completely glucuronidated.
[Uses]

JWH-018 (Indole-d5) N-Pentyl-5-carboxylic Acid is JWH-018 N-Pentyl-5-carboxylic Acid (J211345), a urinary metabolite of JWH-018 (P283650) which acts as an annabinoid receptor.
[Definition]

ChEBI: JWH 018 N-pentanoic acid metabolite is an indolecarboxamide.
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