| Identification | Back Directory | [Name]
Dequalinium chloride hydrate
| [CAS]
1255077-34-9 | [Synonyms]
Dequalinium chloride hydrate >=95% (titration) | [EINECS(EC#)]
803-026-8 | [Molecular Formula]
C30H42ClN4O+ | [MDL Number]
MFCD10567439 | [MOL File]
1255077-34-9.mol | [Molecular Weight]
510.14 |
| Hazard Information | Back Directory | [Biochem/physiol Actions]
Dequalinium chloride is a selective blocker of apamin-sensitive K+ channels and inhibitor of XIAP (X-linked inhibitor of apoptosis protein). Has been shown to induce cytotoxicity in human acute promyelocytic leukemia NB4 cells through disturbance of mitochondrial function, oxidative stress, and downregulation of Raf/MEK/ERK and PI3K/Akt signaling pathways. |
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|