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1256341-22-6

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1256341-22-6 Structure

1256341-22-6 Structure
IdentificationBack Directory
[Name]

2-[[[2-(Tetradecyl)phenyl]amino]carbonyl]benzoic acid
[CAS]

1256341-22-6
[Synonyms]

CX08005
CX08005,CX-08005
CX08005 >=98% (HPLC)
2-[[[2-(Tetradecyl)phenyl]amino]carbonyl]benzoic acid
Benzoic acid, 2-[[[2-(tetradecyloxy)phenyl]amino]carbonyl]-
[Molecular Formula]

C28H39NO4
[MDL Number]

MFCD30480928
[MOL File]

1256341-22-6.mol
[Molecular Weight]

453.61
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
Hazard InformationBack Directory
[Uses]

CX08005 is a competitive PTP1B inhibitor (IC50 = 0.781 μM). Binds catalytic P-loop of enzyme. Improves insulin sensitivity in obese mice in the glucose tolerance test and the homeostasis model assessment of insulin resistance index (HOMA-IR). Enhances insulin-induced glucose uptake in adipocytes and myotubes in vitro. Exhibits some selectivity for PTP1B over other protein tyrosine phosphatases, except TCPTP.
[storage]

Store at -20°C
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