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1257051-63-0

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1257051-63-0 Structure

1257051-63-0 Structure
IdentificationBack Directory
[Name]

THPP-1
[CAS]

1257051-63-0
[Synonyms]

THPP-1
[Molecular Formula]

C23H21ClN6O3
[MOL File]

1257051-63-0.mol
[Molecular Weight]

464.9
Chemical PropertiesBack Directory
[density ]

1.45±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 31.25 mg/mL (67.22 mM)
[form ]

A solid
[pka]

4.70±0.30(Predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Biological Activity]

THPP-1, a chemical probe recommended by SGC, is a potent and orally active inhibitor of phosphodiesterase 10A (PDE10A) with Ki values of 1 nM and 1.3 nM for human and rat, respectively. THPP-1 has good pharmacological properties.
[target]

IC50: 1-1.3 nM (PDE10A).

[storage]

Store at -20°C
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