ChemicalBook--->CAS DataBase List--->1257116-00-9

1257116-00-9

1257116-00-9 Structure

1257116-00-9 Structure
IdentificationBack Directory
[Name]

RQ-00311651
[CAS]

1257116-00-9
[Synonyms]

RQ-00311651
[Molecular Formula]

C19H18F3N5O2
[MOL File]

1257116-00-9.mol
[Molecular Weight]

405.37
Hazard InformationBack Directory
[Description]

RQ-00311651 is a novel T-type Ca2+ channel blocker, in distinct rodent models for neuropathic and visceral pain. RQ-00311651 strongly suppressed T currents when tested at holding potentials of -65 ~ -60 mV, but not -80 mV, in the Cav3.1- or Cav3.2-expressing cells. RQ-00311651 also inhibited high K-induced Ca signaling in those cells.
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