| Identification | Back Directory | [Name]
RO495 | [CAS]
1258296-60-4 | [Synonyms]
RO495
CS-2667
RO495/RO-495
RO495 (TYK Tool 1)
Benzamide, N-[2-[(2-amino-6-methyl-4-pyrimidinyl)amino]-4-pyridinyl]-2,6-dichloro- | [Molecular Formula]
C17H14Cl2N6O | [MDL Number]
MFCD21364479 | [MOL File]
1258296-60-4.mol | [Molecular Weight]
389.24 |
| Chemical Properties | Back Directory | [density ]
1.517±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 78 mg/mL (200.39 mM);Ethanol: Insoluble | [form ]
Solid | [pka]
10.48±0.70(Predicted) | [color ]
Light yellow to yellow | [Water Solubility ]
Water: Insoluble |
| Hazard Information | Back Directory | [Uses]
RO495 is a potent inhibitor of non-receptor tyrosine-protein kinase 2 (TYK2 kinase)[1]. | [References]
[1] Tobie D. Lee, et al. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular Pharmacology November 2019, 96 (5) 629-640. DOI:10.1124/mol.119.115964 |
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Lynnchem
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Novachemistry
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DC Chemicals
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