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126055-13-8

126055-13-8 Structure

126055-13-8 Structure
IdentificationBack Directory
[Name]

CP 102
[CAS]

126055-13-8
[Synonyms]

CP 102
4(1H)-Pyridinone, 2-ethyl-3-hydroxy-1-(2-hydroxyethyl)-
[Molecular Formula]

C9H13NO3
[MDL Number]

MFCD00870477
[MOL File]

126055-13-8.mol
[Molecular Weight]

183.2
Chemical PropertiesBack Directory
[solubility ]

DMF: 1 mg/ml,DMSO: 1 mg/ml,PBS (pH 7.2): 1 mg/ml
[form ]

A solid
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H319-H302-H315-H335
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501
Hazard InformationBack Directory
[Biological Activity]

CP102 is an iron chelator.1,2 It decreases hepatic total non-heme and ferritin-stored iron levels in mice when administered in the drinking water at a concentration of 2 mg/ml.2
[References]

1.Dobbin, P.S., Hider, R.C., Hall, A.D., et al.Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: Orally active iron chelators with clinical potentialJ. Med. Chem.36(17)2448-2458(1993) 2.Smith, A.G., Clothier, B., Francis, J.E., et al.Protoporphyria induced by the orally active iron chelator 1,2-diethyl-3-hydroxypyridin-4-one in C57BL/10ScSn miceBlood89(3)1045-1051(1997)
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