ChemicalBook--->CAS DataBase List--->12607-92-0

12607-92-0

12607-92-0 Structure

12607-92-0 Structure
IdentificationBack Directory
[Name]

Aceglutamide Aluminum
[CAS]

12607-92-0
[Synonyms]

glumal kw 110
Aluminum complex
ALUMINUMACEGLUTAMIDE
Aceglutamide Aluminum
ACEGLUTAMIDE ALUMINIUM
n-acetyl-l-glutamine aluminum salt
PENTAKIS(N-ACETYL-L-GLUTAMINATO)TETRAHYDRO-XYTRIALUMINUM
pentakis(n(sup 2)-acetyl-l-glutaminato)tetrahydroxytri-aluminu
pentakis(n(sup 2)-acetyl-l-glutaminato)tetrahydroxytrialuminum
[Molecular Formula]

C21H33AlN6O12
[MDL Number]

MFCD01674514
[MOL File]

12607-92-0.mol
[Molecular Weight]

588.501
Chemical PropertiesBack Directory
[Melting point ]

221° (dec)
[form ]

solid
Raw materials And Preparation ProductsBack Directory
[Raw materials]

N-Acetyl-L-glutamine
Hazard InformationBack Directory
[Originator]

Glumal ,Kyowa Hakko ,Japan ,1978
[Uses]

Anti-ulcerative.
[Definition]

ChEBI: Aceglutamide aluminum is a glutamine derivative.
[Manufacturing Process]

A mixture of 37.6 g of N-acetyl-L-glutamine and 1,000 ml of water is heated to 40°C, and 900 ml of an isopropanol solution containing 40.8 g of aluminum isopropoxide is added to the warm mixture with stirring. The stirring is continued for 10 minutes. The reaction mixture is filtered and the filtrate is concentrated under reduced pressure. Isopropanol is added to the aqueous solution and the salt precipitates in the solution. The precipitates are collected by filtration and upon drying, 48.5 g of the crystalline-like aluminum salt of Nacetyl- L-glutamine are obtained.
[Brand name]

Glumal (Kyowa Hakko Kogyo Co., Ltd., Japan).
[Therapeutic Function]

Antiulcer
Safety DataBack Directory
[Toxicity]

LD50 in male mice, rats (g/kg): 14.3, >14.5 orally; 5.0, 4.2 i.p.; 0.46, 0.40 i.v. (Kagawa)
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