ChemicalBook--->CAS DataBase List--->1264754-13-3

1264754-13-3

1264754-13-3 Structure

1264754-13-3 Structure
IdentificationBack Directory
[Name]

E3 ligase Ligand 5
[CAS]

1264754-13-3
[Synonyms]

E3 ligase Ligand 5
PROTAC ERRα ligand 1
PROTAC ERRα ligand 1
4-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-2-methoxyphenoxy]-3-(trifluoromethyl)benzonitrile
[Molecular Formula]

C19H11F3N2O4S
[MDL Number]

MFCD29034874
[MOL File]

1264754-13-3.mol
[Molecular Weight]

420.36
Chemical PropertiesBack Directory
[density ]

1.53±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

7.31±0.20(Predicted)
[color ]

Light yellow to green yellow
Hazard InformationBack Directory
[Description]

E3L-4133, also known as E3 ligase Ligand 5, is an E3 ligase Ligand that can be used in PROTAC (proteolysis targeting chimera) technology to engage an E3 ubiquitin ligase. PROTAC is a two-headed molecule capable of removing specific unwanted proteins.
[target]

PROTAC ERRα ligand 1 is an estrogen-related receptor α (ERRα) antagonist.
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