| Identification | Back Directory | [Name]
H-GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-TYR-LEU-OH | [CAS]
126768-94-3 | [Synonyms]
MBP (4-14)
QKRPSQRSKYL
MBP (4-14) (BOVINE)
PKC SUBSTRATE PEPTIDE
MYELIN BASIC PROTEIN (4-14)
MYELIN BASIC PROTEIN (4-14) (2)
PROTEIN KINASE C SUBSTRATE PEPTIDE
MYELIN BASIC PROTEIN FRAGMENT 4-14
MYELIN BASIC PROTEIN (4-14) (BOVINE)
Myelin basic protein (4-14), N-acetylated
BOVINE MYELIN BASIC PROTEIN FRAGMENT 4-14
GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-TYR-LEU
Myelin Basic Protein (4-14)
MBP (4-14) (bovine)
H-GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-TYR-LEU-OH
GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-TYR-LEU: QKRPSQRSKYL
L-Gln-L-Lys-L-Arg-L-Pro-L-Ser-L-Gln-L-Arg-L-Ser-L-Lys-L-Tyr-L-Leu-OH
L-Leucine, L-glutaminyl-L-lysyl-L-arginyl-L-prolyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-lysyl-L-tyrosyl- | [Molecular Formula]
C60H103N21O17 | [MDL Number]
MFCD00133371 | [MOL File]
126768-94-3.mol | [Molecular Weight]
1390.59 |
| Hazard Information | Back Directory | [Uses]
Myelin Basic Protein (MHP4-14), a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca2+/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts[1][2]. | [Biological Activity]
Protein Target: PKC''Target Sub-Family: AGC | [References]
[1] Farrar YJ, et al. A phosphatase resistant substrate for the assay of protein kinase C in crude tissue extracts. Biochem Biophys Res Commun. 1991;180(2):694-701. DOI:10.1016/s0006-291x(05)81121-0
[2] Yasuda I, et al. A synthetic peptide substrate for selective assay of protein kinase C. Biochem Biophys Res Commun. 1990;166(3):1220-1227. DOI:10.1016/0006-291x(90)90996-z |
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