| Identification | Back Directory | [Name]
(2S)-2-(3-((S)-5-amino-1-carboxypentyl)ureido)pentanedioic acid TFA | [CAS]
1269794-89-9 | [Synonyms]
(2S)-2-(3-((S)-5-amino-1-carboxypentyl)ureido)pentanedioic acid TFA
(S)-2-(3-((S)-5-amino-1-carboxypentyl)ureido)pentanedioic acid compound with 2,2,2-trifluoroacetic acid (1:1) | [Molecular Formula]
C14H22F3N3O9 | [MDL Number]
MFCD32901379 | [MOL File]
1269794-89-9.mol | [Molecular Weight]
433.34 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [form ]
Solid | [color ]
White to off-white | [Water Solubility ]
Water : 160 mg/mL (369.23 mM; Need ultrasonic) |
| Hazard Information | Back Directory | [Biological Activity]
GCPII-IN-1 TFA is a glutamate carboxypeptidase II (GCPII, or PSMA) inhibitor scaffold with a Ki of 44.3 nM[1]. | [References]
[1]. Jan Tykvart, et al. Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery. Bioorg Med Chem. 2014 Aug 1;22(15):4099-108. |
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