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127625-29-0

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127625-29-0 Structure

127625-29-0 Structure
IdentificationBack Directory
[Name]

Fananserin
[CAS]

127625-29-0
[Synonyms]

RP-62203
Fananserin
2-[3-[4-(4-Fluorophenyl)piperazino]propyl]-2H-naphth[1,8-cd]isothiazole 1,1-dioxide
2-[3-[4-(4-Fluorophenyl)-1-piperazinyl]propyl]-2H-naphthyl[1,8-cd]isothiazole-1,1-dioxide
2H-Naphth[1,8-cd]isothiazole, 2-[3-[4-(4-fluorophenyl)-1-piperazinyl]propyl]-, 1,1-dioxide
[Molecular Formula]

C23H24FN3O2S
[MDL Number]

MFCD00866648
[MOL File]

127625-29-0.mol
[Molecular Weight]

425.52
Chemical PropertiesBack Directory
[storage temp. ]

Store at RT
[solubility ]

Soluble to 100 mM in DMSO
[form ]

Powder
Hazard InformationBack Directory
[Uses]

Antipsychotic.
[Definition]

ChEBI: LSM-2183 is a sulfonic acid derivative and a member of naphthalenes.
[Biological Activity]

5-HT 2A receptor antagonist that also displays high affinity at D 4 receptors (K i values are 0.26, 2.93, 25, 38, 70 and 726 nM for 5-HT 2A , D 4 , H 1 , α 1 , 5-HT 1A and D 2 receptors respectively). Inhibits inositol phosphate formation evoked by 5-HT in vitro (IC 50 = 7.76 nM) and antagonizes mescaline-induced head twitches in vivo .
Spectrum DetailBack Directory
[Spectrum Detail]

Fananserin(127625-29-0)1HNMR
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