ChemicalBook--->CAS DataBase List--->127685-38-5

127685-38-5

127685-38-5 Structure

127685-38-5 Structure
IdentificationBack Directory
[Name]

cholestanol, 5α,6α-epoxy-d7
[CAS]

127685-38-5
[Synonyms]

5α,6α-epoxycholestanol-d7
cholestanol, 5α,6α-epoxy-d7
cholestanol, 5α,6α-epoxy-d7
5 alfa, 6 alfa-Epoxy-Cholestanol-d7
[Molecular Formula]

C27H46O2
[MDL Number]

MFCD22416997
[MOL File]

127685-38-5.mol
[Molecular Weight]

402.66
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

powder
Hazard InformationBack Directory
[Uses]

Isotope labelled isomer of Cholesterol 5β,6β-epoxide is an oxysterol produced as an oxidation product of cholesterol.
[Biological Activity]

5α,6α-epoxycholestanol (5α,6α-EC) is a liver X receptor (LXR) antagonist. 5α,6α-EC is employed in anticancer treatments. It impairs redox state and affects atherogenesis. The levels of 5α,6α-EC are elevated in hypercholesterolemia. It mediates steroid receptor coactivator (SRC) recruitment.
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