| Identification | Back Directory | [Name]
ASPERFURAN | [CAS]
129277-10-7 | [Synonyms]
ASPERFURAN
3-penta-1,2-dienyl-2,3-dihydro-1-benzofuran-5,7-diol
5,7-BENZOFURANDIOL, 2,3-DIHYDRO-2-(1,3-PENTADIENYL)-, (R-(E,E))- | [Molecular Formula]
C13H14O3 | [MDL Number]
MFCD08274558 | [MOL File]
129277-10-7.mol | [Molecular Weight]
218.25 |
| Hazard Information | Back Directory | [Description]
Asperfuran is a fungal metabolite originally isolated from A. oryzae that has antifungal and anticancer activities. It inhibits the growth of 23 fungi in a disc assay when used at a concentration of 50 μg per disc. Asperfuran inhibits chitin synthase with an IC50 value of 300 μM. It inhibits proliferation of HeLa S3 and L1210 cancer cells (IC50s = 25 μg/ml for both). |
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