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130-49-4

130-49-4 Structure

130-49-4 Structure
IdentificationBack Directory
[Name]

ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE
[CAS]

130-49-4
[Synonyms]

2’-amp
Ado-2'-P
Adenylic Acid Hydrate
adenosine2’-phosphoricacid
adenosine 2'-phosphate hemihydrate
Adenosine Monophosphate 2'(3')-AMP
ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE
2'-, and 3'-adenylic acid, mixed isomers
ADENOSINE 2' -& 3'-MONOPHOSPHATEFREE ACI D
adenosine 2'-3'-monophosphate mixed isomers
Adenosine 2'(3')-Monophosphate(2',3'mixed)
adenosine 2'(3')-monophosphate mixed isomers
Adenosine-2'(3')-monophosphoric acid (mixed isomers)
Adenylic Acid Hydrate (2'- and 3'- mixture) from Yeast
Adenosine 2′- &3′-monophosphate Mixed Isomers disodium salt
Adenosine-2'-monophosphoric acid;Adenosine-2'-phosphoric acid;2-AMP
[EINECS(EC#)]

204-990-7
[Molecular Formula]

C10H14N5O7P
[MDL Number]

MFCD00151215
[MOL File]

130-49-4.mol
[Molecular Weight]

347.223
Chemical PropertiesBack Directory
[Appearance]

colorless or white to yellowish powder
[Melting point ]

183 °C
[Boiling point ]

815.5±75.0 °C(Predicted)
[density ]

2.3200 (rough estimate)
[refractive index ]

1.9050 (estimate)
[storage temp. ]

−20°C
[solubility ]

<3mg/ml in PBS(pH7.2)
[form ]

Solid
[pka]

pK1: 3.81(+1);pK2: 6.17(0) (25°C)
[color ]

White
[biological source]

yeast
[Water Solubility ]

0.5g/L(15 ºC)
[Merck ]

157
Hazard InformationBack Directory
[Chemical Properties]

colorless or white to yellowish powder
[Uses]

Adenosine 2′-monophosphate (2′-AMP) is a metabolite produced from hydrolysis of 2′,3′-cAMP. 2′-AMP inhibits proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. 2′-AMP is used in the synthesis of a new photoaffinity lable for the coenzyme site of porcine NADP-specific isocitrate dehydrogenase. 2′,3′-cAMP and 2′-AMP represent a new unexplored pathway for adenosine-based cell regulation.
[Definition]

ChEBI: Adenosine 2'-phosphate is a purine ribonucleoside 2'-monophosphate. It has a role as a Saccharomyces cerevisiae metabolite. It is a conjugate acid of an adenosine 2'-phosphate(2-).
[Biological Activity]

AMP serves as a key component of several compoundsincluding coenzyme Awhich plays an essential role in energy metabolismas well as certain key redox cofactors such as NAD+NADP+and FAD. FurthermoreAMP is one of the key components of RNAwhich is essential for protein synthesis and other biological processes in cells.
Safety DataBack Directory
[WGK Germany ]

3
[RTECS ]

AU7480300
[Toxicity]

mouse,LD,intraperitoneal,> 1gm/kg (1000mg/kg),Annals of the New York Academy of Sciences. Vol. 60, Pg. 251, 1954.
Spectrum DetailBack Directory
[Spectrum Detail]

ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE(130-49-4)1HNMR
ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE(130-49-4)13CNMR
ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE(130-49-4)IR1
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