ChemicalBook--->CAS DataBase List--->130342-80-2

130342-80-2

130342-80-2 Structure

130342-80-2 Structure
IdentificationBack Directory
[Name]

3-(4-chlorophenyl)tropane-2-carboxylic acid methyl ester
[CAS]

130342-80-2
[Synonyms]

3-(4-chlorophenyl)tropane-2-carboxylic acid methyl ester
[Molecular Formula]

C16H20ClNO2
[MOL File]

130342-80-2.mol
[Molecular Weight]

293.79
Chemical PropertiesBack Directory
[solubility ]

DMF: 20 mg/ml; DMSO: 5 mg/ml; Ethanol: 30 mg/ml
[form ]

A crystalline solid
[Stability:]

Hygroscopic
Hazard InformationBack Directory
[Description]

RTI-31 (Item No. 17977) is an analytical reference standard that is categorized as a tropane. RTI-31 increases self-administration in rhesus monkeys. This product is intended for research and forensic applications.
[Uses]

RTI-COC 31 is a potent phenyltropane cocaine analog which exhibits inhibitory interactions with serotonergic neurons. Also, it is an intermediate used in the synthesis of RTI-113 (R701110), which is a 3-phenyltropane analogue that acts as a potent and selective dopamine uptake inhibitor. RTI-113 has been shown to reduce cocaine self-administration at high occupancy of dopamine transporter. Studies suggest that RTI-113 and its analogs may be useful tools for developing potential agonist therapies for cocaine dependence.
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