| Identification | Back Directory | [Name]
alpha-Terthienylmethal | [CAS]
13059-93-3 | [Synonyms]
α-TerthienylMethanol
α-Terthienylmethanol
alpha-Terthienylmethal
alpha-TerthienylMethanol
[2,2':5',2''-Terthiophene]-5-methanol | [Molecular Formula]
C13H10OS3 | [MDL Number]
MFCD06202658 | [MOL File]
13059-93-3.mol | [Molecular Weight]
278.41 |
| Chemical Properties | Back Directory | [Melting point ]
150-151 °C(Solv: benzene (71-43-2)) | [Boiling point ]
424.7±40.0 °C(Predicted) | [density ]
1.376±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [pka]
13.72±0.10(Predicted) | [color ]
Yellow |
| Hazard Information | Back Directory | [Uses]
α-Terthienylmethanol is a terthiophene isolated from the n-hexane fraction of E. prostrata. α-Terthienylmethanol has potent cytotoxic activity against human endometrial cancer cells (Hec1A and Ishikawa) (IC50 < 1 μM). α-Terthienylmethanol increases the intracellular level of ROS and decreases that of GSH[1]. | [target]
NADPH-oxidase | ROS | [References]
[1] Jae-Seung Lee, et al. α-Terthienylmethanol, isolated from Eclipta prostrata, induces apoptosis by generating reactive oxygen species via NADPH oxidase in human endometrial cancer cells. J Ethnopharmacol. 2015, 169. DOI:10.1016/j.jep.2015.04.029 |
|
| Company Name: |
BioBioPha Co., Ltd.
|
| Tel: |
0871-65217109 13211707573; |
| Website: |
http://www.biobiopha.com |
|