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1307803-52-6

1307803-52-6 Structure

1307803-52-6 Structure
IdentificationBack Directory
[Name]

JWH 073 N-butanoic acid metabolite
[CAS]

1307803-52-6
[Synonyms]

JWH-073 Butanoic Acid
JWH073-butanoic acid metabolite
JWH-073 butanoic acid metabolitb
JWH 073 N-butanoic acid metabolite
1H-Indole-1-butanoic acid, 3-(1-naphthalenylcarbonyl)-
JWH-073 Impurity 3 (JWH-073 N-Butanoic Acid Metabolite)
[Molecular Formula]

C23H19NO3
[MDL Number]

MFCD18382144
[MOL File]

1307803-52-6.mol
[Molecular Weight]

357.4
Chemical PropertiesBack Directory
[Fp ]

9°C
[storage temp. ]

-20°C
[solubility ]

DMF: 10 mg/ml; DMSO: 5 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS (pH 7.2) (1:10): 0.1 mg/ml
[form ]

A crystalline solid
Safety DataBack Directory
[Symbol(GHS) ]


GHS02, GHS06, GHS08
[Signal word ]

Danger
[Hazard statements ]

H225-H301+H311+H331-H370
[Precautionary statements ]

P210-P260-P280-P301+P310-P311
[RIDADR ]

UN1230 - class 3 - PG 2 - Methanol, solution
[WGK Germany ]

1
Hazard InformationBack Directory
[Description]

JWH 073 is a mildly selective agonist of the central cannabinoid (CB1) receptor derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding CB1 and the peripheral cannabinoid (CB2) receptor are 8.9 and 38 nM, respectively for a CB1:CB2 ratio of 0.23. JWH 073 is one of several synthetic CBs which have been included in smoking mixtures. JWH 073 N-butanoic acid metabolite is expected to be a urinary metabolite of JWH 073, characterized by carboxylation of the N-alkyl chain, based on the metabolism of the closely-related JWH 015 and JWH 018. In urine samples, this metabolite of JWH 018 is almost completely glucuronidated.
[Uses]

JWH-073 (Indole-d7) Butanoic Acid is a by-product in the synthesis of JWH-073 (Indole-d5) Butanoic Acid (J211287). JWH-073 (Indole-d5) Butanoic Acid is labelled JWH-073 Butanoic Acid (J211285), a urinary metabolite of JWH-073 (B693550) which acts as a partial agonist at both the CB1 and CB2 cannabinoid receptors.
[Definition]

ChEBI: JWH 073 N-butanoic acid metabolite is an indolecarboxamide.
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