| Identification | Back Directory | [Name]
Poly(oxy-1,2-ethanediyl),α-[4-[[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl]oxy]-1,4-dioxobutyl]-ω-methoxy-Polymer | [CAS]
1309573-60-1 | [Synonyms]
TPGS-750-M
wt. % in H2O
DL-α-Tocopherol methoxypolyethylene glycol succinate
DL-alpha-Tocopherol methoxypolyethylene glycol succinate
DL-α-Tocopherol methoxypolyethylene glycol succinate solution
DL-alpha-Tocopherol methoxypolyethylene glycol succinate solution
DL-α-Tocopherol methoxypolyethylene glycol succinate solution 2 wt. % in H2O
DL-alpha-Tocopherol methoxypolyethylene glycol succinate solution (TPGS-750-M)
DL-alpha-Tocopherol Methoxypolyethylene glycol succinate solution 2 wt. % in H2O
Poly(oxy-1,2-ethanediyl),α-[4-[[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl]oxy]-1,4-dioxobutyl]-ω-methoxy-Polymer
Poly(oxy-1,2-ethanediyl),α-[4-[[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl]oxy]-1,4-dioxobutyl]-ω-methoxy-Polymer | [Molecular Formula]
(C2H4O)nC34H56O5 | [MOL File]
1309573-60-1.mol |
| Chemical Properties | Back Directory | [density ]
0.981 g/mL at 25 °C | [refractive index ]
n20/D1.340 | [Fp ]
>110℃ | [storage temp. ]
Store at -20°C | [form ]
Liquid | [color ]
Colorless to light yellow | [Water Solubility ]
Water: ≥ 50 mg/mL |
| Hazard Information | Back Directory | [Uses]
DL-α-Tocopherol methoxypolyethylene glycol succinate (TPGS-750-M), a biodegradable and water-soluble derivative of natural vitamin E, is used as an environmentally benign nonionic surfactant in metal-catalyzed cross-coupling reactions in water. It is used in Heck, Suzuki-Miyaura, Sonogashira, and Negishi like couplings reactions. It can also be utilized in aminations, C-H activations, and olefin metathesis reactions.
TPGS-750-M can also be employed in:
- The nucleophilic aromatic substitution reaction of aryl and heteroaryl halides with nitrogen, oxygen, and sulfur nucleophiles under mild conditions.
- The preparation of quinoxaline-2,3 diones from quinoxalinones via C(sp2)-H hydroxylation reaction.
- The intramolecular N-arylation of amines using a copper catalyst.
| [Uses]
Second generation amphiphile which forms micelles upon dissolution in water allowing a variety of cross-coupling reactions to take place in water instead of organic solvent.
Included among the possible reactions are:
- Olefin metathesis
- Pd-catalyzed cross coupling reactions including Heck, Suzuki-Miyaura, Sonogashira and Buchwald-Hartwig reactions
- C-H activation reactions
Second generation amphiphile for cross-coupling reactions in water | [General Description]
This product TPGS-750-M is a lead surfactant for many transition metal-catalyzed cross-couplings and has been enhanced for catalytic efficiency. |
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|