ChemicalBook--->CAS DataBase List--->132458-33-4

132458-33-4

132458-33-4 Structure

132458-33-4 Structure
IdentificationBack Directory
[Name]

Spironolactone EP Impurity A
[CAS]

132458-33-4
[Synonyms]

Δ20-Spironolactone
Spiranolactone IMP A
Spironolactone Impurity A
Spiranolactone Impurity A
Spironolactone EP Impurity A
20,21-Dehydro Spironolactone
Spironolactone EP Impurity A (Delta-20-Spironolactone)
Spironolactone Impurity 1(Spironolactone EP Impurity A)
Pregna-4,20-diene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, γ-lactone, (7α,17α)- (9CI)
S-[(2′R)-3,5′-dioxo-5′H-spiro[androst-4-ene-17,2′-furan]-7α-yl] ethanethioate (Δ20-spironolactone)
Spironolactone Related Compound B ((2''R)-7alpha-(Acetylthio)-5''H-spiro[androst-4-ene-17,2''-furan]-3 (1619028)
S-((7S,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl)ethanethioate
S-((2'R,7R,8R,9S,10R,13S,14S)-10,13-Dimethyl-3,5'-dioxo-1,2,3,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl) ethanethioate (Spironolactone Impurity)
[Molecular Formula]

C24H30O4S
[MOL File]

132458-33-4.mol
[Molecular Weight]

414.56
Chemical PropertiesBack Directory
[Melting point ]

205-208°C
[Boiling point ]

603.0±55.0 °C(Predicted)
[density ]

1.25±0.1 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Off-White
[Stability:]

Hygroscopic
Safety DataBack Directory
[HS Code ]

2937290000
Hazard InformationBack Directory
[Uses]

20,21-Dehydro Spironolactone (Spironolactone EP Impurity A) is an impurity of Spironolactone (S683000), a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome.
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