| Identification | Back Directory | [Name]
Compound L | [CAS]
1326852-06-5 | [Synonyms]
7-[[2-(3
STL127705
Compound L
4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimido[4
7-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione
DNA-PKCS kinase,inhibit,STL 127705,STL127705,H1299 cells,DNA-dependent protein kinase,STL-127705,DNA-PK,Inhibitor,antiproliferative,Apoptosis,SF-767 cells,anticancer | [Molecular Formula]
C22H20FN5O4 | [MDL Number]
MFCD20740645 | [MOL File]
1326852-06-5.mol | [Molecular Weight]
437.42 |
| Chemical Properties | Back Directory | [Boiling point ]
605.2±65.0 °C(Predicted) | [density ]
1.40±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
|DMSO : 2.4 mg/mL (5.49 mM; Need ultrasonic) | [form ]
Solid | [pka]
-1.93±0.20(Predicted) | [color ]
Off-white to light yellow | [Water Solubility ]
Water : 100 mg/mL (228.61 mM; Need ultrasonic) |
| Hazard Information | Back Directory | [Uses]
7-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione is a small-molecular inhibitor of Ku70/80 protein used in the treatmentment of cancer and other diseases. |
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