ChemicalBook--->CAS DataBase List--->132746-60-2

132746-60-2

132746-60-2 Structure

132746-60-2 Structure
IdentificationBack Directory
[Name]

CP 96345
[CAS]

132746-60-2
[Synonyms]

CP 96345
CP-96345-1
(2S)-N-(2-Methoxybenzyl)-2β-benzhydryl-1-azabicyclo[2.2.2]octane-3β-amine
(2S)-2β-Diphenylmethyl-3β-(2-methoxybenzylamino)-1-azabicyclo[2.2.2]octane
(2S)-2β-(Diphenylmethyl)-N-(2-methoxybenzyl)-1-azabicyclo[2.2.2]octan-3β-amine
(2S,3S)-N-(2-Methoxyphenyl)methyl-2-diphenylmethyl-1-azabicyclo[2.2.2]octan-3-amine
(2S)-2β-(Diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3β-amine
(2S,3S)-2-(DiphenylMethyl)-N-[(2-Methoxyphenyl)Methyl]-1-azabicyclo[2.2.2]octan-3-aMine
(2S-cis)-2-(DiphenylMethyl)-N-[(2-Methoxyphenyl)Methyl]- 1-azabicyclo[2.2.2]octan-3-aMine
1-Azabicyclo[2.2.2]octan-3-amine, 2-(diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-, (2S,3S)-
(2S,3S)-cis-2-(Diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine
[Molecular Formula]

C28H32N2O
[MDL Number]

MFCD00900615
[MOL File]

132746-60-2.mol
[Molecular Weight]

412.57
Chemical PropertiesBack Directory
[storage temp. ]

room temp
[solubility ]

DMSO: soluble24mg/mL
[form ]

white powder
[color ]

Off-white to light yellow
Safety DataBack Directory
[Hazard Codes ]

Xn,N
[Risk Statements ]

22-36/37/38-50/53
[Safety Statements ]

26-60-61
[RIDADR ]

UN 3077 9 / PGIII
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

CP 96345 is a potent and selective non-peptide NK1 receptor antagonist (1,2,3). CP 96345 attenuates substance P-induced salivary response and inhibits neurogenic inflammation in vivo.
[Uses]

CP 96345 is a potent and selective non-peptide NK1 receptor antagonist. CP 96345 attenuates substance P-induced salivary response and inhibits neurogenic inflammation in vivo.
[Biological Activity]

Potent and selective non-peptide NK 1 receptor antagonist. Attenuates substance P-induced salivary response and inhibits neurogenic inflammation in vivo .
[Biochem/physiol Actions]

CP-96345 is a selective NK1 antagonist. CP96345 inhibits substance P-induced salivation in the rat by classical in vivo bioassay, but did not inhibit NK2, NK3, or numerous other receptors.
[storage]

Store at -20°C
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