| Identification | Back Directory | [Name]
Mal-PEG8-COOH | [CAS]
1334177-86-4 | [Synonyms]
Mal-PEG8-COOH
Mal-NH-PEG8-COOH
Mal-NH-PEG8-acid
MAL-AMIDO-PEG8-COOH
maleimide-PEG8-acid
Mal-amido-PEG8-acid
Mal-amido-PEG8-C2-acid
Mal-NH-PEG8-CH2CH2COOH
MALEIMIDE-NH-PEG8-CH2CH2COOH
Mal-amido-PEG8-propionic Acid
Maleimide-PEG8-propionic acid
1-Maleimido-3-oxo-7,10,13,16,19,22,25,28-octaoxa-4-aza-hentriacontan-31-oic acid
31-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacontanoic Acid
1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22,25,28-octaoxa-4-azahentriacontan-31-oic acid
4,7,10,13,16,19,22,25-Octaoxa-28-azahentriacontanoic acid, 31-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo- | [Molecular Formula]
C26H44N2O13 | [MDL Number]
MFCD13184956 | [MOL File]
1334177-86-4.mol | [Molecular Weight]
592.63 |
| Chemical Properties | Back Directory | [Boiling point ]
747.9±60.0 °C(Predicted) | [density ]
1?+-.0.06 g/cm3(Predicted) | [form ]
Solid-Liquid Mixture | [pka]
4.28±0.10(Predicted) | [color ]
Colorless to off-white |
| Hazard Information | Back Directory | [Description]
Mal-amido-PEG8-acid is a PEG linker containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. | [Uses]
31-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacontanoic Acid is reactant in the light-induced endosomal lysis events in fibroblast, normal, and carcinoma cell lines using a colloidal mesoporous silica (CMS) nanoparticle. | [IC 50]
Non-cleavable Linker |
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