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1334782-79-4

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1334782-79-4 Structure

1334782-79-4 Structure
IdentificationBack Directory
[Name]

PF-5190457
[CAS]

1334782-79-4
[Synonyms]

PF-5190457
PF-05190457
PF-05190457 >=95% (HPLC)
1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone
[Molecular Formula]

C29H32N6OS
[MOL File]

1334782-79-4.mol
[Molecular Weight]

512.67
Chemical PropertiesBack Directory
[storage temp. ]

room temp
[solubility ]

DMSO: 250 mg/mL (487.64 mM)
[form ]

powder
[color ]

white to beige
[optical activity]

[α]/D +45 to +55°, c = 0.5 in methanol
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319
[Precautionary statements ]

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard InformationBack Directory
[Uses]

PF 5190457 is a potent, selective, and orally bioavailable ghrelin receptor inverse agonist.
[Biochem/physiol Actions]

PF-05190457 is an orally available, potent and selective ghrelin receptor inverse agonist. PF-05190457 potently increases insulin secretion in glucose-stimulated human islets.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

PF-5190457(1334782-79-4)1HNMR
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