| Identification | Back Directory | [Name]
TYRPHOSTIN B44 | [CAS]
133550-32-0 | [Synonyms]
AG 527
Zinc03871437
TYRPHOSTIN B44
TYRPHOSTIN B44(-)
TRYPHOSTIN AG 527
TYRPHOSTIN AG 527
Reaxys ID: 4356230
ALPHA-CYANO-(-)-(R)-N-(ALPHA-PHENETHYL)-3,4-DIHYDROXYCINNAMIDE
(-)-(r)-n-(α-methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide
(-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXYBENZYLIDINECYANOACETAMIDE
(-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXY-BENZYLIDENECYANOACETAMIDE
(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phenylethyl]-2-propenamide
(R)-(E)-2-CYANO-3-(3',4'-DIHYDROXYPHENYL)-N-(1-PHENYLETHYL)-2-PROPENAMIDE
Tyrphostin B44, (-)-(R)-N-(α-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide | [Molecular Formula]
C18H16N2O3 | [MDL Number]
MFCD00209854 | [MOL File]
133550-32-0.mol | [Molecular Weight]
308.33 |
| Hazard Information | Back Directory | [Uses]
Tyrphostin B44, (-) enantiomer is a potent inhibitor of (EGFR) kinase. | [Biological Activity]
Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC 50 = 0.4 μ M), more active than the (+) enantiomer ((S)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide ). Selective over ErbB2. |
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| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Tel: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
MOLEKULA Ltd.
|
| Tel: |
+44 (0) 1747 831066 |
| Website: |
www.molekula.co.uk |
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