Identification | Back Directory | [Name]
5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one | [CAS]
133627-17-5 | [Synonyms]
BIRH 414 BIRH 414 BS Nevirapine EP Impurity A Nevirapine Related CoMpound A 11-Ethyl-4-methyl-5,11-dihydro-6H-d Nevirapine Related Compound A (15 mg) Nevirapine EP Impurity A/ Nevirapine Related Compound A 11-Ethyl-5H-dipyrido[3,2-b:2'',3''-e][1,4]diazepin-6(11H)-one 11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one 11-Ethyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one 6H-Dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 11-ethyl-5,11-dihydro-4-methyl- Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Nevirapine impurity Ⅱ{11-ethyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2′,3′-e][1,4] diazepin-6-one} Nevirapine impurity Ⅱ
{11-ethyl-4-methyl-5,11-dihydr o-6H-dipyrido[3,2-b:2′,3′
-e][1,4] diazepin-6-one} Nevirapine Related Compound A (15 mg) (5,11-dihydro-6H-11-ethyl-4-methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one) | [Molecular Formula]
C14H14N4O | [MDL Number]
MFCD27967300 | [MOL File]
133627-17-5.mol | [Molecular Weight]
254.29 |
Chemical Properties | Back Directory | [Melting point ]
212-214℃ (1,2-dichloroethane ) | [Boiling point ]
389.8±42.0 °C(Predicted) | [density ]
1.224±0.06 g/cm3(Predicted) | [pka]
12.05±0.20(Predicted) |
Hazard Information | Back Directory | [Uses]
BIRH 414 is an derivative of 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine, a highly potent inhibitor of wild-type human immunodeficiency virus type 1. BIRH 414 was also shown to exhibit binding affinity towards HIV-1 reverse transcriptase enzyme.
This is also an impurity found in Nevirapine (N391275). |
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