| Identification | Back Directory | [Name]
11-Cyclopropyl-5,11-dihydro-4-(hydroxyMethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]
diazepin-6-one | [CAS]
133627-24-4 | [Synonyms]
Nevirapine 12-Hydroxy
12-Hydroxy Nevirapine D4
12-Hydroxy Nevirapine D7
11-cyclopropyl-4-(hydroxymethyl)-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one
N11-Cyclopropyl-4-hydroxymethyl-5,11-dihydro-6H-dipyrido(3,2-b:2,3-e)(1,4)diazepin-6-one
11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2,3-e][1,4]\ndiazepin-6-one
11-Cyclopropyl-5,11-dihydro-4-(hydroxyMethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]
diazepin-6-one
6H-Dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 11-cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-
12-Hydroxy NevirapineQ: What is
12-Hydroxy Nevirapine Q: What is the CAS Number of
12-Hydroxy Nevirapine Q: What is the storage condition of
12-Hydroxy Nevirapine | [Molecular Formula]
C15H14N4O2 | [MOL File]
133627-24-4.mol | [Molecular Weight]
282.3 |
| Chemical Properties | Back Directory | [Melting point ]
>184oC (dec.) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Pale Yellow to Light Brown |
| Hazard Information | Back Directory | [Uses]
11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2'',3''-e][1,4]diazepin-6-one, is a metabolite of Nevirapine (N391275), which is a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. It is also an antiviral. | [Uses]
11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, is a metabolite of Nevirapine (N391275), which is a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. It is also an antiviral.
| [Definition]
ChEBI: 12-hydroxynevirapine is a dipyridodiazepine that is nevirapine in which one of the hydrogens of the methyl group has been substituted by a hydroxy group. It is a metabolite of the anti-HIV drug, nevirapine. It has a role as a drug metabolite. It is a member of cyclopropanes, a dipyridodiazepine and an aromatic primary alcohol. It is functionally related to a nevirapine. |
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Energy Chemical
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http://www.energy-chemical.com |
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