ChemicalBook--->CAS DataBase List--->133628-73-6

133628-73-6

133628-73-6 Structure

133628-73-6 Structure
IdentificationBack Directory
[Name]

H-ASP(AMC)-OH
[CAS]

133628-73-6
[Synonyms]

H-ASP(AMC)-OH
L-Asp(AMC)-OH
ASPARTIC ACID(AMC)-OH
-(7-Amido-4-methylcoumarin)
L-ASPARTIC ACID BETA-(7-AMIDO-4-METHYLCO
L-ASPARTIC ACID B-(7-AMIDO4-METHYLCOUMAR IN)
L-Aspartic acid 4-(4-methyl-7-coumarinylamide)
l-aspartic acid β-(4-methyl-7-coumarinylamide)
L-ASPARTIC ACID BETA-(7-AMIDO-4-METHYLCOUMARIN)
L-Aspartic acid β-7-amido-4-methylcoumarin≥ 99% (HPLC)
L-Asparagine, N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
L-ASPARTIC ACID ALPHA-(7-AMIDO-4-METHYLCOUMARIN) 1-HYDRATE
L-Aspartic acid β-(7-aMido-4-MethylcouMarin) fluorescent aMino acid
L-Aspartic acid β-(4-methyl-7-coumarinylamide), L-Aspartic acid 4-(4-methyl-7-coumarinylamide)
[Molecular Formula]

C14H14N2O5
[MDL Number]

MFCD00236804
[MOL File]

133628-73-6.mol
[Molecular Weight]

290.27
Chemical PropertiesBack Directory
[Boiling point ]

610.0±55.0 °C(Predicted)
[density ]

1.452±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

1 M HCl: 10 mg/mL, clear, faintly yellow
[form ]

Solid
[pka]

2.32±0.10(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
Hazard InformationBack Directory
[Chemical Properties]

White crystalline powder
[Uses]

L-Aspartic Acid β-(7-Amido-4-methylcoumarin) is sensitive fluorogenic substrate used in lysosomal glycoasparaginase assays. This assay is good for diagnosis of aspartylglycosaaminuria.
[Biological Activity]

L-Aspartic acid β-(7-amido-4-methylcoumarin) is used as a fluorogenic substrate for studying the specificity and kinetics of lysosomal glycoasparaginase(s) (aspartylglucosaminidase) and L-asparaginase(s).''L-Aspartic acid-β-7-amido-4-methylcoumarin is sensitive and specific fluorogenic substrate used to assay for lysosomal glycoasparaginase (aspartylglucosaminidase) activity and the diagnosis of aspartylglucosaminuria.
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