ChemicalBook--->CAS DataBase List--->1347750-78-0

1347750-78-0

1347750-78-0 Structure

1347750-78-0 Structure
IdentificationBack Directory
[Name]

t-Boc-N-amido-PEG5-acid
[CAS]

1347750-78-0
[Synonyms]

BocNH-P5-COOH
BOC-PEG5-CH2CH2COOH
Boc-N-amido-PEG5-acid
T-BOC-NH-AMIDO-PEG5-COOH
t-boc-N-amido-PEG5-propionic acid
2,2-Dimethyl-4-oxo-3,8,11,14,17,20-hexaoxa-5-azatricosan-23-oic acid
5,8,11,14,17-Pentaoxa-2-azaeicosanedioic acid, 1-(1,1-dimethylethyl) ester
[Molecular Formula]

C18H35NO9
[MDL Number]

MFCD24539478
[MOL File]

1347750-78-0.mol
[Molecular Weight]

409.47
Chemical PropertiesBack Directory
[Boiling point ]

536.9±50.0 °C(Predicted)
[density ]

1.123±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[pka]

4.28±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Description]

t-Boc-N-amido-PEG5-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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