| Identification | Back Directory | [Name]
Bis-Propargyl-PEG13 | [CAS]
1351373-50-6 | [Synonyms]
1351373-50-6
CAS_1351373-50-6
Bis-Propargyl-PEG13
Bis-propargyl-PEG12
4,7,10,13,16,19,22,25,28,31,34,37,40-Tridecaoxatritetraconta-1,42-diyne | [Molecular Formula]
C30H54O13 | [MDL Number]
MFCD28334510 | [MOL File]
1351373-50-6.mol | [Molecular Weight]
622.74 |
| Hazard Information | Back Directory | [Description]
Bis-propargyl-PEG13 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | [in vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. | [structure and hydrogen bonding]
Bis-propargyl-PEG13 comprises two propargyl groups which can form triazole linkages with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions. The hydrophilic PEG units help improve the solubility of the molecule in aqueous media. |
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| Company Name: |
Henan Alfachem Co.,Ltd.
|
| Tel: |
0371-0371-0371-55051623 18137891487 |
| Website: |
www.chemicalbook.com/supplier/14555231/ |
| Company Name: |
Wuhan Topule
|
| Tel: |
+86-02787215551 +86-19945035818 |
| Website: |
http://www.topule.com/ |
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