| Identification | Back Directory | [Name]
S-acetyl-PEG6-alcohol | [CAS]
1352221-63-6 | [Synonyms]
AcS-PEG6-OH
S-acetyl-PEG6
S-acetyl-PEG6-OH
S-acetyl-PEG6-alcohol
Ethanethioic acid, S-(17-hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl) ester | [Molecular Formula]
C14H28O7S | [MDL Number]
MFCD22574786 | [MOL File]
1352221-63-6.mol | [Molecular Weight]
340.43 |
| Hazard Information | Back Directory | [Biological Activity]
S-acetyl-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | [References]
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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