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136056-02-5

136056-02-5 Structure

136056-02-5 Structure
IdentificationBack Directory
[Name]

L-PHENYLALANINE (3-13C)
[CAS]

136056-02-5
[Synonyms]

L-PHENYLALANINE (3-13C)
L-PHENYLALANINE-BETA-13C
L-PHENYLALANINE-BETA-13C, 99 ATOM % 13C
(2S)-2-amino-3-phenyl(3^{13}C)propanoic acid
[Molecular Formula]

C9H11NO2
[MDL Number]

MFCD00084040
[MOL File]

136056-02-5.mol
[Molecular Weight]

166.2
Chemical PropertiesBack Directory
[Melting point ]

270-275 °C (dec.)(lit.)
[form ]

Solid
[color ]

White to off-white
[optical activity]

[α]25/D -33.0°, c = 1 in H2O
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

L-Phenylalanine-3-13C is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
[IC 50]

NMDA Receptor
[References]

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
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