ChemicalBook--->CAS DataBase List--->1365287-97-3

1365287-97-3

1365287-97-3 Structure

1365287-97-3 Structure
IdentificationBack Directory
[Name]

Emibetuzumab
[CAS]

1365287-97-3
[Synonyms]

Emibetuzumab
Emibetuzumab (anti-MET)
Research Grade Emibetuzumab(DHC34201)
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Description]

Emibetuzumab is a bivalent antibody that blocks HGF- and MET-receptor interaction, leading to MET internalization and degradation.
[Clinical Use]

A phase I study determined a tolerable dose for emibetuzumab to be 700–2000 mg as a monotherapy and in combination with erlotinib in NSCLC patients. It is currently being investigated in phase II in combination with erlotinib.
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