ChemicalBook--->CAS DataBase List--->136765-48-5

136765-48-5

136765-48-5 Structure

136765-48-5 Structure
IdentificationBack Directory
[Name]

NORTRIPTYLINE-D3 HYDROCHLORIDE
[CAS]

136765-48-5
[Synonyms]

Nortriptyline-d3
Reaxys ID: 2152475
[2H3]-Nortriptyline
NORTRIPTYLINE HCL (D3)
NORTRIPTYLINE HCL (METHYL-D3)
NORTRIPTYLINE-D3 HYDROCHLORIDE
NORTRIPTYLINE-D3 HCL (N-METHYL-D3)
Nortriptyline-D3 hydrochloride solution
NORTRIPTYLINE-D3HYDROCHLORIDE,100/ML(FREEBASE)INMETHANOL
Nortriptyline (D3, 98%) 1.0 mg/ml In Methanol (As Free Base)
NORTRIPTYLINE HCL (D3, 98%) 1.0 MG/ML IN METHANOL (AS FREE BASE)
1-Propanamine, 3-(10,11-dihydro-5H-dibenzoa,dcyclohepten-5-ylidene)-N-(methyl-d3)-
[EINECS(EC#)]

802-964-5
[Molecular Formula]

C19H19ClD3N
[MDL Number]

MFCD00198172
[MOL File]

136765-48-5.mol
[Molecular Weight]

302.86
Chemical PropertiesBack Directory
[Fp ]

9℃
[storage temp. ]

-20°C
[form ]

liquid
Safety DataBack Directory
[Hazard Codes ]

F,T
[Risk Statements ]

11-23/24/25-39/23/24/25
[Safety Statements ]

7-16-36/37-45
[RIDADR ]

UN1230 - class 3 - PG 2 - Methanol, solution
[WGK Germany ]

2
Hazard InformationBack Directory
[Uses]

  • Mass spectrometry standard: Nortriptyline-D3 hydrochloride solution is utilized as a high-precision internal standard in mass spectrometry to quantify nortriptyline levels in biological samples, essential for clinical pharmacokinetic studies and therapeutic drug monitoring.
  • Metabolite research: As a stable isotope-labeled nortriptyline, it aids in metabolite profiling, helping researchers identify and quantify nortriptyline metabolites in various matrices, which is crucial for understanding drug metabolism and disposition.
  • Pharmacokinetic studies: The solution is applied in pharmacokinetic research to assess the absorption, distribution, metabolism, and excretion (ADME) of nortriptyline, providing insights into the drugμs efficacy and safety profiles.
  • Quantitative analysis: In bioanalytical research, Nortriptyline-D3 hydrochloride serves as a standard in developing and validating analytical methods, ensuring accuracy and reproducibility in the quantification of nortriptyline in pharmaceutical formulations and clinical samples.
[General Description]

Nortriptyline is a second generation tricyclic antidepressant (TCA) marketed under trade names such as Sensoval, Aventyl?, and Pamelor? for treatment of major depression. Nortriptyline is also an active metabolite of the TCA amitriptyline. This certified Snap-N-Spike? Solution is suitable as an internal standard for quantitation of nortriptyline levels by LC/MS or GC/MS in clinical toxicology, forensic analysis, urine drug testing, isotope dilution methods, or medication monitoring applications.
136765-48-5 suppliers list
Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Website: https://www.sigmaaldrich.cn
Company Name: Cambridge Isotope Laboratories, Inc.  
Tel: 978 749-8000
Website: www.isotope.com
Company Name: Shanghai Hao Zhun Biological Technology Co., Ltd.  
Tel: 15800340161
Website: www.zzsrm.com
Company Name: Riedel-de Haen AG  
Tel: 800 558-9160
Website: www.sigmaaldrich.com
Company Name: Cerilliant Corporation  
Tel: 800 848 7837 (US and Canada)
Website: www.cerilliant.com
Company Name: Advance Scientific & Chemical  
Tel: (954) 327-0900
Website: www.advance-scientific.com
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