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136846-20-3

136846-20-3 Structure

136846-20-3 Structure
IdentificationBack Directory
[Name]

5'-Epi-LaMivudine
[CAS]

136846-20-3
[Synonyms]

-cystosine
(-)-(2S,5S)-1-<
5'-Epi-LaMivudine
2'-Epi-LaMivudine
Lamivudine-001-SS
Lamivudine 2-Epimer
(+) - trans-lamivudine
Lamivudine Diastereoisomer
2-(hydroxymethyl)-1,3-oxathiolan-5-yl>
Lamivudine EP Impurity B(Enantiomer Mixture)
Lamivudine Impurity 4 (Lamivudine Diastereoisomer)
trans(-)-2-HydroxyMethyl-5-(cytosin-1-yl)-1,3-oxathiolane
(-)-(2S,5S)-1-<2-(hydroxymethyl)-1,3-oxathiolan-5-yl>-cystosine
4-AMino-1-[(2S,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone
4-AMino-1-[(2RS,5RS)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone
2(1H)-Pyrimidinone, 4-amino-1-[(2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-
(2S-trans)-4-AMino-1-[2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone
Lamivudine ImpurityⅥ:4-AMino-1-[(2S,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone
Lamivudine Impurit Ⅱ:(Lamivudine enantiomer (+) - trans-lamivudine)4-AMino-1-[(2S,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone
Lamivudine ImpurityⅡ:(Lamivudine enantiomer (+) - trans-lamivudine)4-AMino-1-[(2RS,5RS)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone
[Molecular Formula]

C8H11N3O3S
[MDL Number]

MFCD00866921
[MOL File]

136846-20-3.mol
[Molecular Weight]

229.26
Chemical PropertiesBack Directory
[Melting point ]

172.6 °C(Solv: water (7732-18-5); methanol (67-56-1))
[Boiling point ]

475.4±55.0 °C(Predicted)
[density ]

1.73±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

DMSO (Slightly), Water (Slightly)
[form ]

Solid
[pka]

13.83±0.10(Predicted)
[color ]

Off-White to Pale Yellow
Hazard InformationBack Directory
[Uses]

2’-Epi-Lamivudine (Lamivudine EP Impurity B) is an epimer of Lamivudine (L172500); an antiviral that inhibits HIV-reverse transcriptase.
[Uses]

An epimer of Lamivudine (L172500); an antiviral that inhibits HIV-reverse transcriptase.
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