| Identification | Back Directory | [Name]
Elbasvir | [CAS]
1370468-36-2 | [Synonyms]
Elbasvir
Albasvir
Elbasvir/MK-8742
MK-8742 Elbasvir
MK-8742; MK8742; MK 8742
Carbamic acid, N,N'-[[(6S)-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazine-3,10-diyl]bis[1H-imidazole-5,2-diyl-(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl]]]bis-, C,C'-dimethyl ester | [Molecular Formula]
C49H55N9O7 | [MDL Number]
MFCD28124343 | [MOL File]
1370468-36-2.mol | [Molecular Weight]
882.017 |
| Chemical Properties | Back Directory | [density ]
1.40±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMF: 33 mg/ml; DMSO: 20 mgm/l; Ethanol: 33 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/ml | [form ]
A crystalline solid | [pka]
11.22±0.46(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Uses]
Elbasvir is a pharmaceutical drug that is used in the treatment of hepatitis C virus in patients with HCV genotype 1 infection. It inhibits an important viral phosphoprotein, NS5A, which is involved in viral replication, assembly, and secretion. | [Definition]
ChEBI: A complex organic heterotetracyclic compound that is a hepatitis C virus nonstructural protein 5A inhibitor used in combination with grazoprevir (under the brand name Zepatier) for treatment of chronic HCV genotypes 1 or 4 infection in adults. |
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