| Identification | Back Directory | [Name]
TC-2153 | [CAS]
1381769-23-8 | [Synonyms]
TC-2153
TC-2153 >=95% (HPLC)
benzopentathiepin 8-(trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine hydrochloride | [Molecular Formula]
C7H5ClF3NS5 | [MDL Number]
MFCD28976193 | [MOL File]
1381769-23-8.mol | [Molecular Weight]
355.87 |
| Hazard Information | Back Directory | [Biochem/physiol Actions]
TC-2153 is a potent inhibitor of STEP (STriatal-Enriched protein tyrosine Phosphatase) that forms a reversible covalent bond with the catalytic cysteine in STEP. TC-2153 increases tyrosine phosphorylation of STEP substrates ERK1/2, Pyk2, and GluN2B in cell cultures. TC-2153 improves cognitive function in transgenic AD mice. |
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| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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DC Chemicals
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https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm |
| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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