| Hazard Information | Back Directory | [Description]
The structure of this alkaloid has recently been revised to that given above in
which the hydroxyl group is placed at C-1. The stereochemistry has also been
determined by Japanese workers. | [Definition]
ChEBI: Ankorine is a pyridoisoquinoline that is 1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline which is substituted at positions 2, 3, and 8 by 2-hydroxyethyl, ethyl, and hydroxy groups, respectively, and by methoxy groups at positions 9 and 10 (the 2R,3R,11bS stereoisomer). It is a benzo[a]quinolizidine alkaloid isolated from the Indian medicinal plant Alangium lamarckii. It has a role as a plant metabolite. It is a member of isoquinolines, a member of phenols, a tertiary amino compound, an aromatic ether, a primary alcohol, an isoquinoline alkaloid and a pyridoisoquinoline. | [References]
Szantay, Szentirmay, Szabb, Tetrahedron Lett., 3725 (1974)
Stereochemistry:
Fujii, Yoshifuji, Yamada, Tetrahedron Lett., 1527 (1975)
Y oshifuji, Fujii, ibid, 1965 (1975) |
|
|