ChemicalBook--->CAS DataBase List--->139141-12-1

139141-12-1

139141-12-1 Structure

139141-12-1 Structure
IdentificationBack Directory
[Name]

CAY10512
[CAS]

139141-12-1
[Synonyms]

CAY10512
1-fluoro-2-[(E)-2-(4-methoxyphenyl)ethenyl]benzene
Benzene, 1-fluoro-2-[(1E)-2-(4-methoxyphenyl)ethenyl]-
NF-kB Activation Inhibitor IV - CAS 139141-12-1 - Calbiochem
[Molecular Formula]

C15H13FO
[MDL Number]

MFCD12912333
[MOL File]

139141-12-1.mol
[Molecular Weight]

228.262
Chemical PropertiesBack Directory
[Melting point ]

100-101 °C
[Boiling point ]

340.4±11.0 °C(Predicted)
[density ]

1.136±0.06 g/cm3(Predicted)
[storage temp. ]

+2C to +8C
[solubility ]

DMF: 3 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.3 mg/ml; DMSO: 2 mg/ml; Ethanol: 0.5 mg/ml
[form ]

Crystalline solid
Hazard InformationBack Directory
[General Description]

A cell-permeable trans-stilbene Resveratrol (Cat. No. 554325) analog that exhibits much enhanced anti-inflammatory potency, but no anti-oxidant activity. Suppresses LPS-induced COX-2 mRNA expression in BV-2 cells (~46% inhibition at 150 nM) and Shown to be ~130-fold more potent than Resveratrol in inhibiting TNF-α-stimulated NF-κB reporter activity in 293T cells (IC50 = 150 nM).
[Biochem/physiol Actions]

Cell permeable: yes
[storage]

Store at -20°C
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