Identification | Back Directory | [Name]
CAY10512 | [CAS]
139141-12-1 | [Synonyms]
CAY10512 1-fluoro-2-[(E)-2-(4-methoxyphenyl)ethenyl]benzene Benzene, 1-fluoro-2-[(1E)-2-(4-methoxyphenyl)ethenyl]- NF-kB Activation Inhibitor IV - CAS 139141-12-1 - Calbiochem | [Molecular Formula]
C15H13FO | [MDL Number]
MFCD12912333 | [MOL File]
139141-12-1.mol | [Molecular Weight]
228.262 |
Chemical Properties | Back Directory | [Melting point ]
100-101 °C | [Boiling point ]
340.4±11.0 °C(Predicted) | [density ]
1.136±0.06 g/cm3(Predicted) | [storage temp. ]
+2C to +8C | [solubility ]
DMF: 3 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.3 mg/ml; DMSO: 2 mg/ml; Ethanol: 0.5 mg/ml | [form ]
Crystalline solid |
Hazard Information | Back Directory | [General Description]
A cell-permeable trans-stilbene Resveratrol (Cat. No. 554325) analog that exhibits much enhanced anti-inflammatory potency, but no anti-oxidant activity. Suppresses LPS-induced COX-2 mRNA expression in BV-2 cells (~46% inhibition at 150 nM) and Shown to be ~130-fold more potent than Resveratrol in inhibiting TNF-α-stimulated NF-κB reporter activity in 293T cells (IC50 = 150 nM). | [Biochem/physiol Actions]
Cell permeable: yes | [storage]
Store at -20°C |
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