ChemicalBook--->CAS DataBase List--->139144-12-0

139144-12-0

139144-12-0 Structure

139144-12-0 Structure
IdentificationBack Directory
[Name]

ISOVALERYL-L-CARNITINE CHLORIDE
[CAS]

139144-12-0
[Synonyms]

ISOVALERYL-L-CARNITINE CHLORIDE
L-CARNITINE:HCL, O-ISOVALERYL UNLABELED
Isovaleryl-L-carnitine-d3 HCl (N-methyl-d3)
[Molecular Formula]

C12H22ClNO3
[MDL Number]

MFCD09263554
[MOL File]

139144-12-0.mol
[Molecular Weight]

263.761
Chemical PropertiesBack Directory
[Melting point ]

>160°C (dec.)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

Methanol (Slightly), Water (Slightly, Heated)
[form ]

Solid
[color ]

White to Off-White
[Stability:]

Hygroscopic
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H319-H317
[Precautionary statements ]

P261-P264-P272-P280-P302+P352-P305+P351+P338-P333+P313-P321-P337+P313-P363-P501
Hazard InformationBack Directory
[Description]

Isovaleryl-L-carnitine is a naturally occurring acylcarnitine that is formed via metabolic conversion of L-leucine. It increases survival and decreases apoptosis in hepatocyte growth factor-deprived murine C2.8 hepatocytes when used at a concentration of 1 mM. Isovaleryl-L-carnitine inhibits amino acid deprivation-induced proteolysis and autophagy in isolated perfused rat liver when used at concentrations of 77 and 100 μM, respectively. Increased levels of isovaleryl carnitine are associated with isovaleryl-CoA dehydrogenase deficiency (isovaleric acidemia).
[Uses]

Isovaleryl L-Carnitine Chloride is used to prepare carnitine benzyl esters as neuroprotectant prodrugs.
[storage]

Store at -20°C
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