ChemicalBook--->CAS DataBase List--->1391712-60-9

1391712-60-9

1391712-60-9 Structure

1391712-60-9 Structure
IdentificationBack Directory
[Name]

CEP-37440
[CAS]

1391712-60-9
[Synonyms]

CS-1603
CEP-37440
CEP37440;CEP 37440
2-(5-chloro-2-{(S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-ylamino}pyrimidin-4-ylamino)-N-methylbenzamide
(S)-2-((5-chloro-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide
2-[[5-Chloro-2-[[(6S)-6,7,8,9-tetrahydro-6-[4-(2-hydroxyethyl)-1-piperazinyl]-1-methoxy-5H-benzocyclohepten-2-yl]amino]-4-pyrimidinyl]amino]-N-methylbenzamide
Benzamide, 2-[[5-chloro-2-[[(6S)-6,7,8,9-tetrahydro-6-[4-(2-hydroxyethyl)-1-piperazinyl]-1-methoxy-5H-benzocyclohepten-2-yl]amino]-4-pyrimidinyl]amino]-N-methyl-
inhibit,Inhibitor,Cluster of differentiation 246,PTK2,triple-negative breast cancer,inflammatory breast cancer,CEP-37440,Anaplastic lymphoma kinase,FAK1,Anaplastic lymphoma kinase (ALK),Focal adhesion kinase,CEP 37440,PTK2 protein tyrosine kinase 2,autophosphorylation kinase,CD246,FAK,ALK tyrosine kinase receptor
[EINECS(EC#)]

200-258-5
[Molecular Formula]

C30H38ClN7O3
[MDL Number]

MFCD28009441
[MOL File]

1391712-60-9.mol
[Molecular Weight]

580.12
Chemical PropertiesBack Directory
[density ]

1.300±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C(protect from light)
[solubility ]

DMF: 12 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml
[form ]

A crystalline solid
[pka]

14.57±0.46(Predicted)
[color ]

Light yellow to yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P280-P305+P351+P338
Hazard InformationBack Directory
[Uses]

CEP-37440 is a highly potent, selective and orally active inhibitor of ALK.
Spectrum DetailBack Directory
[Spectrum Detail]

CEP-37440(1391712-60-9)1HNMR
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