| Identification | Back Directory | [Name]
2-mercapto-1-(4-methoxyphenyl)ethanone | [CAS]
139488-44-1 | [Synonyms]
2-mercapto-1-(4-methoxyphenyl)ethanone
Ethanone, 2-mercapto-1-(4-methoxyphenyl)- | [Molecular Formula]
C9H10O2S | [MDL Number]
MFCD17215991 | [MOL File]
139488-44-1.mol | [Molecular Weight]
182.24 |
| Hazard Information | Back Directory | [Preparation]
Facile displacement of the bromide in 2-bromo-1-(4-methoxyphenyl)ethanone with potassium thioacetate delivered the corresponding thioacyl analog, which was easily hydrolyzed to the free thiol. Obtained in two steps: First, reaction of potassium thioacetate with 2-bromo-1-(4-methoxyphenyl)ethanone in THF at 40° for 24 h (99%), then treatment of the thioacyl derivative so obtained with 1 M sodium hydroxide in methanol at r.t. for 1 h (84%). |
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