| Identification | Back Directory | [Name]
enopeptin A | [CAS]
139601-96-0 | [Synonyms]
enopeptin A
ODKIYTBYJKALOK-BKZRIAMSSA-N
N-[[(2E,4E,6E,8E,10E)-12-(2-Hydroxy-5-oxo-1-cyclopentenylamino)-1,12-dioxo-2,4,6,8,10-dodecapentenyl]-L-Phe-]cyclo[L-Ser*-L-Pro-N-methyl-L-Ala-L-Ala-4β-methyl-L-Pro-] | [Molecular Formula]
C47H57N7O11 | [MOL File]
139601-96-0.mol | [Molecular Weight]
896.005 |
| Hazard Information | Back Directory | [Uses]
Enopeptin A is a depsipeptide antibiotic. It is effective against Gram-positive bacteria and Gram-negative bacteria. However, it is not inhibitory to fungi. | [Uses]
Enopeptin A is an unusual depsipeptide featuring a pentaenone side chain, reported as an antiviral by researchers at RIKEN in 1991. Enopeptin A has potent antibacterial activity against Gram positive and Gram negative bacteria, including MRSA. Enopeptin A is the most non-polar of the acyldepsipeptide (ADEP) antibiotics which include the recently rediscovered compounds, A54556 A and B, that act by activating and disregulating Clp-family proteins. |
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