ChemicalBook--->CAS DataBase List--->1400191-52-7

1400191-52-7

1400191-52-7 Structure

1400191-52-7 Structure
IdentificationBack Directory
[Name]

DBCO-sulfo-SE
[CAS]

1400191-52-7
[Synonyms]

DBCO-sulfo-SE
DBCO-sulfo-NHS ester
DBCO-C6-Sulfo-NHS ester
DBCO-Sulfo-NHS ester sodium
DBCO-sulfo-NHS ester,DBCO-sulfo-SE
Dibenzocyclooctyne-sulfo-N-hydroxysuccinimidyl ester
[Molecular Formula]

C25H21N2NaO8S
[MDL Number]

MFCD22572669
[MOL File]

1400191-52-7.mol
[Molecular Weight]

532.498
Chemical PropertiesBack Directory
[Melting point ]

240-260 °C
[storage temp. ]

-20°C
[form ]

Solid
[color ]

Off-white to yellow
[InChIKey]

NSZPURPXEZOXPC-UHFFFAOYSA-N
[SMILES]

C(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)(=O)CCCCC(=O)ON1C(CC(S(O)(=O)=O)C1=O)=O.[NaH]
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Description]

DBCO-Sulfo-NHS ester is a water-soluble sulfocated reagent containing DBCO moiety. It can be used for simple and efficient labeling of antibodies, proteins and any other primary amine-bearing macromolecules with DBCO moiety in 100% aqueous buffers. DBCO is commonly used for copper-free Click Chemistry reactions.
[Uses]

Dibenzocyclooctyne-sulfo-N-hydroxysuccinimidyl ester may be used for the covalent modification of nano-sized metal-organic frameworks (NMOFs) with nucleic acids via click chemistry during the synthesis stimuli-responsive DNA-gated NMOFs. These NMOFs can act as carriers of a fluorescent agent or anticancer drug, making them highly useful in targeted drug release system.
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