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1400974-23-3

1400974-23-3 Structure

1400974-23-3 Structure
IdentificationBack Directory
[Name]

N-cis-octadec-9Z-enoyl-L-Homoserine lactone Exclusive
[CAS]

1400974-23-3
[Synonyms]

N-cis-octadec-9-enoyl-L-Homoserine lactone
(Z)-N-[(3S)-2-oxooxolan-3-yl]octadec-9-enamide
N-cis-octadec-9Z-enoyl-L-Homoserine lactone Exclusive
[Molecular Formula]

C22H39NO3
[MOL File]

1400974-23-3.mol
[Molecular Weight]

365.55
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH7.2) 1:1: 0.5 mg/ml
[form ]

A crystalline solid
Hazard InformationBack Directory
[Description]

Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group) and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family. C18:1-Δ9 cis-(L)-HSL is a long-chain AHL that may have antimicrobial activity and thus, might be used to inhibit pathogenesis by regulating bacerial quorum sensing signaling.
[storage]

Store at -20°C
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