ChemicalBook--->CAS DataBase List--->1402837-76-6

1402837-76-6

1402837-76-6 Structure

1402837-76-6 Structure
IdentificationBack Directory
[Name]

IDO-IN-6
[CAS]

1402837-76-6
[Synonyms]

IDO-IN-6
NLG-1486
IDO inhibitor 6
IDOIN6,IDO IN 6
5H-Imidazo[5,1-a]isoindole-5-ethanol, 6-fluoro-α-(trans-4-hydroxycyclohexyl)-, (αS,5S)-
[Molecular Formula]

C18H21FN2O2
[MDL Number]

MFCD30207887
[MOL File]

1402837-76-6.mol
[Molecular Weight]

316.38
Chemical PropertiesBack Directory
[Boiling point ]

555.4±35.0 °C(Predicted)
[density ]

1.42±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 50 mg/mL (158.04 mM)
[form ]

Solid
[pka]

14.66±0.20(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

IDO-IN-6 (NLG-1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, Compound 1486, has an IC50 of <1 μM.

IDO-IN-6 (Compound 1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of <1 μM (this is the concentration of IDO-IN-6 at which inhibits 50% of enzymatic activity using recombinant human IDO)[1].

[References]

[1]. Mautino, et al. Preparation of fused imidazole derivatives as IDO inhibitors. From PCT Int. Appl. (2012), 20121018.

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